Mouse Anti-GCM1 Recombinant Antibody (CBLG1-814) (V2LY-1225-LY933)

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Basic Information

Host Animal
Mouse
Clone
CBLG1-814
Application
WB
Immunogen
Full length human recombinant protein of human GCM1.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
ApplicationNote
WB1:2,000

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, BSA, glycerol
Preservative
Sodium azide
Concentration
1 mg/ml
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Glial Cells Missing Homolog 1
Entrez Gene ID
UniProt ID
Function
Transcription factor involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes (PubMed:10542267, PubMed:18160678).

Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer (PubMed:10542267).

Binds to the SYDE1 promoter (PubMed:27917469).

Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (PubMed:19219068).
Biological Process
Anatomical structure morphogenesis Source: ProtInc
Astrocyte fate commitment Source: Ensembl
Branching involved in labyrinthine layer morphogenesis Source: Ensembl
Cell differentiation involved in embryonic placenta development Source: GO_Central
Gliogenesis Source: GO_Central
Positive regulation of syncytium formation by plasma membrane fusion Source: Ensembl
Positive regulation of transcription, DNA-templated Source: MGI
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of cell differentiation involved in embryonic placenta development Source: UniProtKB
Regulation of transcription, DNA-templated Source: MGI
Regulation of transcription by RNA polymerase II Source: GO_Central
Transcription by RNA polymerase II Source: UniProtKB
Cellular Location
Nucleus
PTM
Polyubiquitinated in the presence of UBE2D2 and FBXW2 (in vitro).
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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