Mouse Anti-GLRX2 Recombinant Antibody (CBFYH-0392) (V2LY-1225-LY1520)

Name: Mouse Anti-GLRX2 Recombinant Antibody (CBFYH-0392)
SKU: V2LY-1225-LY1520
Rating: 5 (1 reviews)

See all GLRX2 antibodies

Compare Online Inquiry

Datasheet

SDS

Request for COA

Datasheet Target Q & As Review & reward Protocols Associated Products

Basic Information

Host Animal

Mouse

Clone

CBFYH-0392

Application

ELISA, WB

Immunogen

Full-length recombinant GLRX2.

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2a, κ

Clonality

Monoclonal

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Liquid

Buffer

PBS

Preservative

None

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

More Infomation

Target

Full Name

glutaredoxin 2

Entrez Gene ID

51022

UniProt ID

Q9NS18

Function

Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.

Biological Process

Aging Source: Ensembl
Apoptotic process Source: UniProtKB
Cell differentiation Source: UniProtKB
Cell redox homeostasis Source: UniProtKB
Cellular response to superoxide Source: Ensembl
DNA protection Source: UniProtKB
Glutathione metabolic process Source: UniProtKB
Regulation of signal transduction Source: UniProtKB
Regulation of transcription, DNA-templated Source: UniProtKB
Response to hydrogen peroxide Source: UniProtKB
Response to organic substance Source: UniProtKB
Response to redox state Source: UniProtKB
Response to temperature stimulus Source: UniProtKB

Cellular Location

Isoform 1: Mitochondrion
Isoform 2: Nucleus

Ask a question We look forward to hearing from you.

0 reviews or Q&As

Purchasing FAQs
Technical FAQs

Have you used Mouse Anti-GLRX2 Recombinant Antibody (CBFYH-0392)?
Submit a review and get a Coupon or an Amazon gift card. 20% off Coupon

$30 eGift Card
Submit a review

Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Mouse Anti-GLRX2 Recombinant Antibody (CBFYH-0392) (CAT#: CBMAB-H1263-FY)

Related Products

Mouse Anti-GLRX2 Recombinant Antibody (CBFYH-0392) (CAT#: CBMAB-H1263-FY)

Mouse Anti-GLRX2 Recombinant Antibody (CBLG1-129) (CAT#: CBMAB-G0528-LY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

Online Inquiry

Request bulk or custom quote Second antibody and isotype control

Contact us

Tel: (USA)
(UK)
Fax:

Global Locations

Email:

Online Inquiry