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GRIN2C Matched Antibody Pair (500) (APMAB-500LY)


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Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Rabbit anti-GRIN2C polyclonal antibody, 100 ug
Detection Antibody
Anti-GRIN2C Mouse polyclonal antibody, 40 ul
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of ionotropic glutamate receptor. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Alternative Names
Glutamate Ionotropic Receptor NMDA Type Subunit 2C; Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2C; Glutamate [NMDA] Receptor Subunit Epsilon-3; N-Methyl D-Aspartate Receptor Subtype 2C; NMDAR2C; GluN2C; NR2C; N-Methyl-D-Aspartate Receptor Subunit 2C; Glutamate Receptor Ionotropic, NMDA 2C;
Entrez Gene ID
2905
UniProt ID
Q14957
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For research use only. Not intended for any clinical use.

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