Human Recombinant PIK3R3 protein, His Tag (V2LY-0526-LY6180)

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Basic Information

Expressed Host
Baculovirus-Insect Cells
Protein Species
Human
Tag
His Tag
Protein Construction
This product is Human Recombinant PIK3R3 protein, His Tag consist of Amino Acid: Full Length and predicts a molecular mass of 61 kDa.
Molecule Mass
61 kDa
Sequence
Amino Acid: Full Length
Species
Human

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity
Batch dependent.
Endotoxin
Please contact us for more information.
Format
Liquid
Buffer
PBS
Preservative
None
Storage
Store product at -70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
More Infomation

Target

Full Name
phosphoinositide-3-kinase regulatory subunit 3
Function
Binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1.
Biological Process
B cell differentiation1 PublicationIC:ComplexPortal
Cell migration involved in sprouting angiogenesisManual Assertion Based On ExperimentIGI:BHF-UCL
Immune response1 PublicationIC:ComplexPortal
Insulin receptor signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Negative regulation of anoikis1 PublicationIC:ComplexPortal
Phosphatidylinositol phosphate biosynthetic processManual Assertion Based On ExperimentIBA:GO_Central
Positive regulation of cell migration1 PublicationNAS:ARUK-UCL
Positive regulation of gene expressionManual Assertion Based On ExperimentIMP:BHF-UCL
Positive regulation of protein phosphorylationManual Assertion Based On ExperimentIMP:BHF-UCL
Protein kinase B signalingManual Assertion Based On ExperimentIMP:BHF-UCL
Regulation of phosphatidylinositol 3-kinase activityManual Assertion Based On ExperimentIBA:GO_Central
T cell differentiation1 PublicationIC:ComplexPortal
Cellular Location
cytosol
phosphatidylinositol 3-kinase complex
phosphatidylinositol 3-kinase complex, class IA
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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