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Mouse Anti-GYPC Recombinant Antibody (CBLG1-2185) (V2LY-0226-LY2198)

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Basic Information

Host Animal
Mouse
Clone
CBLG1-2185
Application
WB, ELISA
Immunogen
GYPC (aa 1-57) partial recombinant protein.
Host Species
Mouse
Specificity
Human
Antibody Isotype
IgG1, κ
Clonality
Monoclonal

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS
Preservative
None
Concentration
Batch dependent
Purity
> 95% Purity determined by SDS-PAGE.
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
More Infomation

Target

Full Name
Glycophorin C (Gerbich Blood Group)
Entrez Gene ID
2995
UniProt ID
P04921
Function
This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites are most likely located within the extracellular domain. Glycophorin-C plays an important role in regulating the stability of red cells.
Cellular Location
Cell membrane. Linked to the membrane via band 4.1.
Topology
Extracellular: 1-57
Helical: 58-81
Cytoplasmic: 82-128
PTM
O-glycosylated with core 1 or possibly core 8 glycans.

Rahman, M. S., Biswas, P. K., Saha, S. K., & Moni, M. A. (2022). Identification of glycophorin C as a prognostic marker for human breast cancer using bioinformatic analysis. Network Modeling Analysis in Health Informatics and Bioinformatics, 11(1), 7.

Lin, J. J., Loucks, C. M., Trueman, J. N., Drögemöller, B. I., Wright, G. E., Yoshida, E. M., ... & Carleton, B. C. (2021). Novel variant in glycophorin c gene protects against ribavirin-induced anemia during chronic hepatitis C treatment. Biomedicine & Pharmacotherapy, 143, 112195.

Karatas, M., Ulusan, M., & Demokan, S. (2021). P-10 Methylation-Based Expression Loss of Glycophorin C (GYPC) Gene and Clinical Importance in Oral Cancer. Oral Oncology, 118, 4.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

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Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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