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NFIC Matched Antibody Pair (794) (APMAB-794LY)

This antibody pair set can be used for detecting and quantifying protein level of human NFIC.
See all NFIC antibodies

Specifications

ApplIcation
Sandwich ELISA
Specificity
Human
Capture Antibody
Mouse anti-NFIC monoclonal antibody, 100 ug
Detection Antibody
Anti-NFIC Rabbit polyclonal antibody, 50 ug
Dilutions
10 ng/ml-100 ng/ml
Format
Liquid
Storage
Aliquot and store at -20°Cor -80°C. Avoid freeze-thaw cycles.
Introduction
The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Alternative Names
Nuclear Factor I C; Nuclear Factor I/C (CCAAT-Binding Transcription Factor); CCAAT-Box-Binding Transcription Factor; TGGCA-Binding Protein; NF-I/C; NF1-C; CTF; NFI;
Entrez Gene ID
4782
UniProt ID
P08651

Wu, J., Wang, M., Zhang, Y., Liu, G., & Xing, Y. (2024). Activation of CHPF by transcription factor NFIC promotes NLRP3 activation during the progression of colorectal cancer. Functional & Integrative Genomics, 24(1), 1-13.

Rastogi, N., Gonzalez, J. B. M., Srivastava, V. K., Alanazi, B., Alanazi, R. N., Hughes, O. M., ... & Tonks, A. (2023). Nuclear factor IC overexpression promotes monocytic development and cell survival in acute myeloid leukemia. Leukemia, 37(2), 276-287.

Shukla, V., Wang, H., Varticovski, L., Baek, S., Wang, R., Echtenkamp, F. J., ... & Schrump, D. S. (2023). MA09. 04 Genome-wide Analysis Identifies Nuclear Factor IC as a Novel Transcription Factor and Potential Therapeutic Target in SCLC. Journal of Thoracic Oncology, 18(11), S129-S130.

Cobo, I., Paliwal, S., Bodas, C., Felipe, I., Melià-Alomà, J., Torres, A., ... & Real, F. X. (2023). NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation. Nature Communications, 14(1), 3761.

Xu, C., Xie, X., Zhao, L., Wu, Y., & Wang, J. (2022). The critical role of nuclear factor I‐C in tooth development. Oral Diseases, 28(8), 2093-2099.

Lee, D. S., Song, Y. J., Gug, H. R., Lee, J. H., Bae, H. S., & Park, J. C. (2022). Nuclear Factor IC Regulates Stemness Genes and Proliferation of Stem Cells in Various Mineralized Tissue through Epithelial-Mesenchymal Interactions in Dental Epithelial Stem Cells. Stem Cells International, 2022.

Zhang, H., Luo, Z., Tang, J., Tian, J., Xiao, Y., Sun, C., & Wang, T. (2022). Transcription factor NFIC functions as a tumor suppressor in lung squamous cell carcinoma progression by modulating lncRNA CASC2. Cell Cycle, 21(1), 63-73.

Huang, W., Huang, T., Liu, Y., Fu, J., Wei, X., Liu, D., ... & Yuan, Z. (2021). Nuclear factor IC disrupts cellular homeostasis between autophagy and apoptosis via miR-200b-Ambra1 in neural tube defects. Cell death & disease, 13(1), 17.

Lee, D. S., Roh, S. Y., Choi, H., & Park, J. C. (2020). NFI-C is required for epiphyseal chondrocyte proliferation during postnatal cartilage development. Molecules and Cells, 43(8), 739.

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For research use only. Not intended for any clinical use.

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