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NFIC

The protein encoded by this gene belongs to the CTF/NF-I family. These are dimeric DNA-binding proteins, and function as cellular transcription factors and as replication factors for adenovirus DNA replication. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Full Name
Nuclear Factor I C
Function
Recognizes and binds the palindromic sequence 5'-TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
Biological Process
DNA replicationIEA:UniProtKB-KW
Negative regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:UniProtKB
Positive regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIDA:UniProtKB
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Transcription by RNA polymerase IIManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Nucleus
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Anti-NFIC antibodies

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Mouse Anti-NFIC Recombinant Antibody (CBT109) (V2LY-0625-LY3794)

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Target: NFIC
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat, Cattle, Chicken, Pig
Clone: CBT109
Application*: WB
Datasheet SDS

NFIC Matched Antibody Pair (794) (APMAB-794LY)

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Target: NFIC
Specificity: Human
Datasheet SDS

Mouse Anti-NFIC Recombinant Antibody (A1338) (CBMAB-AP12624LY)

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Target: NFIC
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: A1338
Application*: ICC, WB
Datasheet SDS

Mouse Anti-NFIC Recombinant Antibody (A1337) (CBMAB-AP5087LY)

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Target: NFIC
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: A1337
Application*: ICC, WB
Datasheet SDS

Mouse Anti-NFIC Recombinant Antibody (4E10-D8-F4) (CBMAB-Z0400-LY)

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Target: NFIC
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 4E10-D8-F4
Application*: WB, IC
Datasheet SDS

Mouse Anti-NFIC Recombinant Antibody (CBWJN-1373) (CBMAB-N2230-WJ)

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Target: NFIC
Host: Mouse
Specificity: Human
Clone: CBWJN-1373
Application*: WB
Datasheet SDS

Mouse Anti-NFIC Recombinant Antibody (CBWJN-0415) (CBMAB-N2229-WJ)

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Target: NFIC
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Mouse, Rat, Chicken, Cattle, Human, Pig
Clone: CBWJN-0415
Application*: WB, IC
Datasheet SDS

Mouse Anti-NFIC Recombinant Antibody (2C3) (CBMAB-N2228-WJ)

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Target: NFIC
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2C3
Application*: E, WB
Datasheet SDS

Mouse Anti-NFIC Recombinant Antibody (1C12-2A2) (CBMAB-N2226-WJ)

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Target: NFIC
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1C12-2A2
Application*: E, IF, IH, WB
Datasheet SDS

Mouse Anti-NFIC Recombinant Antibody (4E10) (CBMAB-N2225-WJ)

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Target: NFIC
Host: Mouse
Specificity: Human
Clone: 4E10
Application*: IC, WB
Datasheet SDS

Mouse Anti-NFIC Recombinant Antibody (CBWJN-0394) (CBMAB-N0321-WJ)

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Target: NFIC
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBWJN-0394
Application*: DB, WB
Datasheet SDS

Mouse Anti-NFIC Recombinant Antibody (1D6) (CBMAB-N0320-WJ)

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Target: NFIC
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 1D6
Application*: E, WB
Datasheet SDS
More Infomation
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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