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B2M

This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The encoded antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.[provided by RefSeq, Aug 2014]B2M (Beta-2-Microglobulin) is a Protein Coding gene. Diseases associated with B2M include Immunodeficiency 43 and Amyloidosis, Familial Visceral. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System. Gene Ontology (GO) annotations related to this gene include identical protein binding.Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553).

Anti-B2M antibodies

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Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-1651
Application*: F
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-1685
Application*: C, IA, R
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-1800
Application*: F, IP, WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-1819
Application*: F, IF, IH
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-1830
Application*: E
Target: B2M
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-1863
Application*: E, IP
Target: B2M
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-1966
Application*: F, IF
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-2008
Application*: E, F, P, WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYY-2058
Application*: E, IF, P, RNAi, WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-2062
Application*: E, WB, P, IF, F
Target: B2M
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-2064
Application*: E
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-2071
Application*: E, WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-2107
Application*: E, F, IC, P, WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Chicken
Clone: CBYY-2127
Application*: F, IH, IP, WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-0039
Application*: E, WB, P
Target: B2M
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYY-0040
Application*: WB
Target: B2M
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBYY-0041
Application*: P
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-0042
Application*: E, IH
Target: B2M
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-0044
Application*: E, WB, IH, IP, F, R
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Pig
Clone: CBYY-0045
Application*: E, WB, IH, F
Target: B2M
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-0046
Application*: E
Target: B2M
Host: Mouse
Antibody Isotype: IgM
Specificity: Rabbit
Clone: CBYY-0047
Application*: F
Target: B2M
Host: Mouse
Specificity: Human
Clone: CBYY-0049
Application*: E, F, IH, WB
Target: B2M
Host: Mouse
Specificity: Human
Clone: CBYY-0050
Application*: E, F, IC, IH, WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-0059
Application*: E
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rabbit
Clone: CBYY-0061
Application*: F, IH, WB
Target: B2M
Host: Rat
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-0062
Application*: F
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-0063
Application*: E, WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-0065
Application*: WB, IH
Target: B2M
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-0067
Application*: E
Target: B2M
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-2143
Application*: E, F, IH, IP, WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYY-2149
Application*: E
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-0051
Application*: E, P, WB
Target: B2M
Host: Mouse
Antibody Isotype: IgM
Specificity: Rat
Clone: CBYY-0053
Application*: F
Target: B2M
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-0054
Application*: F, IF
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-0055
Application*: E, P
Target: B2M
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYY-0056
Application*: WB, E
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-0057
Application*: F
Target: B2M
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-0058
Application*: E
Target: B2M
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYM-0877
Application*: E, F
Target: B2M
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYM-0878
Application*: E, F, IP, R, WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 9E10
Application*: WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Application*: ELISA, WB, IHC, IP
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 12B2
Application*: ELISA
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CB173A
Application*: ELISA, IHC
Target: B2M
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0345
Application*: WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0346
Application*: WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0347
Application*: WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0348
Application*: WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0349
Application*: WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0350
Application*: E
Target: B2M
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0493
Target: B2M
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYR0494
Application*: SE
Target: B2M
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYR0495
Target: B2M
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: BBM.1
Application*: F, IH, IP, FN
Target: B2M
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2D3E5
Application*: E, IH
Target: B2M
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 3F9-2C2
Application*: WB, E
Target: B2M
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Monkey
Clone: 2H10
Application*: FC, IHC, WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: B2M/961
Application*: FC, IF, IHC
Target: B2M
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: BBM.1
Application*: FC, IF, IHC
Target: B2M
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CAP212
Application*: IHC
Target: B2M
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: D8
Application*: ICC, IHC, IP, WB
Target: B2M
Host: Rat
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CAP213
Application*: ICC, IHC, IP, WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CAP214
Application*: ICC, IHC, IP, WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CAP211
Application*: ELISA, IHC
Target: B2M
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 8E1
Application*: ELISA, IHC, WB
Target: B2M
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 246-E9.E7
Application*: FC, IF
Target: B2M
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: SPM374
Application*: FC, IF
Target: B2M
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: C21.48A1
Application*: FC, IF
Target: B2M
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: SPM617
Application*: FC, IF, IHC
Target: B2M
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: B2M/1118
Application*: FC, IF, IHC
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)