CNN1
CNN1 (Calponin 1) is a Protein Coding gene. Diseases associated with CNN1 include Laryngeal Small Cell Carcinoma and Infantile Digital Fibromatosis. Among its related pathways are Myometrial Relaxation and Contraction Pathways and Endothelin Pathways. Gene Ontology (GO) annotations related to this gene include actin binding and calmodulin binding. An important paralog of this gene is CNN3.
Full Name
Calponin 1
Function
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).
Biological Process
Actomyosin structure organization Source: InterPro
Negative regulation of vascular associated smooth muscle cell proliferation Source: BHF-UCL
Regulation of smooth muscle contraction Source: UniProtKB
Negative regulation of vascular associated smooth muscle cell proliferation Source: BHF-UCL
Regulation of smooth muscle contraction Source: UniProtKB
Cellular Location
Cytoskeleton; Focal adhesion
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Anti-CNN1 antibodies
+ Filters

Target: CNN1
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human
Clone: CBXC-0489
Application*: IH, WB, IF
Target: CNN1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2F5-1H4
Application*: E, P, WB
Target: CNN1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: 0-N-39
Application*: WB, IP, IF, P
Target: CNN1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4833
Application*: IH
Target: CNN1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBCNC-224
Application*: P
Target: CNN1
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBWJC-2854
Application*: E, P, WB
Target: CNN1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat
Clone: CBWJC-2853
Application*: IH, IF, F
Target: CNN1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: CBWJC-2047
Application*: IH, IF, F
Target: CNN1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat
Clone: CBXC-2753
Application*: IH, WB, IF, F
Target: CNN1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat
Clone: CBXC-1376
Application*: F, WB, IH
Target: CNN1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat
Clone: CBXC-2706
Application*: F, IF, IH
Target: CNN1
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBYY-C0677
Application*: E, WB
Target: CNN1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-1987
Application*: WB, IP, IF, P
Target: CNN1
Specificity: Human
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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