Sign in or Register

Keywords Search | Target Search

DNAJB1

This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

Full Name

DnaJ Heat Shock Protein Family (Hsp40) Member B1

Function

Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response (PubMed:9499401).

Stimulates ATP hydrolysis and the folding of unfolded proteins mediated by HSPA1A/B (in vitro) (PubMed:24318877).

Biological Process

Chaperone cofactor-dependent protein refolding Source: UniProtKB
Forebrain development Source: Ensembl
Negative regulation of inclusion body assembly Source: UniProtKB
Negative regulation of transcription by RNA polymerase II Source: GO_Central
Negative regulation of transcription from RNA polymerase II promoter in response to stress Source: UniProtKB
Positive regulation of ATPase activity Source: BHF-UCL
Regulation of cellular response to heat Source: Reactome
Response to unfolded protein Source: ProtInc

Cellular Location

Nucleus; Nucleolus; Cytoplasm. Translocates rapidly from the cytoplasm to the nucleus, and especially to the nucleoli, upon heat shock.

Anti-DNAJB1 antibodies

Mouse Anti-DNAJB1 Recombinant Antibody (A114) (CBMAB-AP10033LY)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Yeast

Clone: A114

Application*: ELISA, IP, WB

Mouse Anti-DNAJB1 Recombinant Antibody (A115) (CBMAB-AP10043LY)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Yeast

Clone: A115

Application*: ELISA, IP, WB

Mouse Anti-DNAJB1 Recombinant Antibody (A116) (CBMAB-AP10044LY)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Yeast

Clone: A116

Application*: ELISA, IP, WB

Mouse Anti-DNAJB1 Recombinant Antibody (A118) (CBMAB-AP10025LY)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat

Clone: A118

Application*: ICC/IF, ELISA, IHC, IP, WB

Mouse Anti-DNAJB1 Recombinant Antibody (1A12) (CBMAB-D1273-YC)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1A12

Application*: F

Mouse Anti-DNAJB1 Recombinant Antibody (1B12) (CBMAB-D1274-YC)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1B12

Application*: F, IF, WB

Mouse Anti-DNAJB1 Recombinant Antibody (1E10) (CBMAB-D1275-YC)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 1E10

Application*: F, WB

Mouse Anti-DNAJB1 Recombinant Antibody (1E9) (CBMAB-D1276-YC)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 1E9

Application*: WB, IH, IF, F

Mouse Anti-DNAJB1 Recombinant Antibody (1F9) (CBMAB-D1277-YC)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human, Dog

Clone: 1F9

Application*: WB, IH, IF, F

Mouse Anti-DNAJB1 Recombinant Antibody (1G4) (CBMAB-D1278-YC)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 1G4

Application*: F

Mouse Anti-DNAJB1 Recombinant Antibody (1H8) (CBMAB-D1279-YC)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 1H8

Application*: F, WB

Mouse Anti-DNAJB1 Recombinant Antibody (2E1) (CBMAB-D1280-YC)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 2E1

Application*: IP, WB

Mouse Anti-DNAJB1 Recombinant Antibody (3B9.E6) (CBMAB-D1281-YC)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse, Rat

Clone: 3B9.E6

Application*: WB

Mouse Anti-DNAJB1 Recombinant Antibody (7H250) (CBMAB-D1282-YC)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human, Mouse, Rat

Clone: 7H250

Application*: WB

Mouse Anti-DNAJB1 Recombinant Antibody (1G10.H8) (CBMAB-H0990-FY)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human, Mouse, Rat, Yeast

Clone: 1G10.H8

Application*: E, WB, IP

Rabbit Anti-DNAJB1 Recombinant Antibody (G.779.5) (CBMAB-H0991-FY)

SDS

Target: DNAJB1

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: G.779.5

Application*: P, WB

Mouse Anti-DNAJB1 Recombinant Antibody (CBFYH-0129) (CBMAB-H0992-FY)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human, Dog

Clone: CBFYH-0129

Application*: WB, F, IH, IF, P

Mouse Anti-DNAJB1 (AA 1-340) Recombinant Antibody (CBFYH-0130) (CBMAB-H0993-FY)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human, Mouse, Rat

Clone: CBFYH-0130

Application*: WB

Mouse Anti-DNAJB1 (AA 1-340 ) Recombinant Antibody (CBFYH-0131) (CBMAB-H0994-FY)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBFYH-0131

Application*: IP, WB

Mouse Anti-DNAJB1 (AA 1-340) Recombinant Antibody (CBFYH-0133) (CBMAB-H0996-FY)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBFYH-0133

Application*: E, WB

Mouse Anti-DNAJB1 Recombinant Antibody (CBFYH-3404) (CBMAB-H3948-FY)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human, Mouse, Rat

Clone: CBFYH-3404

Application*: IP, WB

Mouse Anti-DNAJB1 Recombinant Antibody (CBFYH-3403) (CBMAB-H3947-FY)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBFYH-3403

Application*: WB, F

Mouse Anti-DNAJB1 Recombinant Antibody (3F200) (CBMAB-D1286-YC)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Monkey, Mouse, Rabbit, Rat

Clone: 3F200

Application*: F, IF, C, IP, WB

Mouse Anti-DNAJB1 Recombinant Antibody (K1C7) (CBMAB-D1285-YC)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: K1C7

Application*: E, WB

Mouse Anti-DNAJB1 Recombinant Antibody (CBYCD-337) (CBMAB-D1283-YC)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG

Specificity: Human

Clone: CBYCD-337

Application*: WB, IC, P, C, E

Mouse Anti-DNAJB1 Recombinant Antibody (A117) (CBMAB-AP10045LY)

SDS

Target: DNAJB1

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Yeast

Clone: A117

Application*: ELISA, IP, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)

Go to
Compare