EN1
Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq]
Full Name
EN1
Biological Process
Adult locomotory behavior Source: Ensembl
Anatomical structure morphogenesis Source: ProtInc
Cerebellum development Source: Ensembl
Dopaminergic neuron differentiation Source: ParkinsonsUK-UCL
Dorsal/ventral pattern formation Source: Ensembl
Drinking behavior Source: Ensembl
Embryonic brain development Source: Ensembl
Embryonic forelimb morphogenesis Source: Ensembl
Midbrain development Source: Ensembl
Midbrain-hindbrain boundary development Source: Ensembl
Motor learning Source: Ensembl
Multicellular organism growth Source: Ensembl
Negative regulation of neuron apoptotic process Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: NTNU_SB
Neuron development Source: Ensembl
Neuron differentiation Source: GO_Central
Pigmentation Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: Ensembl
Proximal/distal pattern formation Source: Ensembl
Rregulation of transcription by RNA polymerase II Source: GO_Central
Response to cocaine Source: Ensembl
Skeletal system development Source: ProtInc
Social behavior Source: Ensembl
Anatomical structure morphogenesis Source: ProtInc
Cerebellum development Source: Ensembl
Dopaminergic neuron differentiation Source: ParkinsonsUK-UCL
Dorsal/ventral pattern formation Source: Ensembl
Drinking behavior Source: Ensembl
Embryonic brain development Source: Ensembl
Embryonic forelimb morphogenesis Source: Ensembl
Midbrain development Source: Ensembl
Midbrain-hindbrain boundary development Source: Ensembl
Motor learning Source: Ensembl
Multicellular organism growth Source: Ensembl
Negative regulation of neuron apoptotic process Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: NTNU_SB
Neuron development Source: Ensembl
Neuron differentiation Source: GO_Central
Pigmentation Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: Ensembl
Proximal/distal pattern formation Source: Ensembl
Rregulation of transcription by RNA polymerase II Source: GO_Central
Response to cocaine Source: Ensembl
Skeletal system development Source: ProtInc
Social behavior Source: Ensembl
Cellular Location
Nucleus
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Anti-EN1 antibodies
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Target: EN1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse
Clone: 1F5
Application*: WB, IH, E
Target: EN1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 4G11
Application*: WB, IP, F
Target: EN1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: 3H2
Application*: E, IP, WB
Target: EN1
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human, Mouse, Rat
Clone: 3G9
Application*: WB, IP, IF, E
Target: EN1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse
Clone: 3E5
Application*: WB, E
Target: EN1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse
Clone: CBFYE-0843
Application*: WB, IH, E
More Infomation
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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