EN1

Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq]

EN1

Adult locomotory behavior Source: Ensembl
Anatomical structure morphogenesis Source: ProtInc
Cerebellum development Source: Ensembl
Dopaminergic neuron differentiation Source: ParkinsonsUK-UCL
Dorsal/ventral pattern formation Source: Ensembl
Drinking behavior Source: Ensembl
Embryonic brain development Source: Ensembl
Embryonic forelimb morphogenesis Source: Ensembl
Midbrain development Source: Ensembl
Midbrain-hindbrain boundary development Source: Ensembl
Motor learning Source: Ensembl
Multicellular organism growth Source: Ensembl
Negative regulation of neuron apoptotic process Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: NTNU_SB
Neuron development Source: Ensembl
Neuron differentiation Source: GO_Central
Pigmentation Source: Ensembl
Positive regulation of transcription by RNA polymerase II Source: Ensembl
Proximal/distal pattern formation Source: Ensembl
Rregulation of transcription by RNA polymerase II Source: GO_Central
Response to cocaine Source: Ensembl
Skeletal system development Source: ProtInc
Social behavior Source: Ensembl

Nucleus