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GAP43

The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Full Name
Growth Associated Protein 43
Function
This protein is associated with nerve growth. It is a major component of the motile 'growth cones' that form the tips of elongating axons. Plays a role in axonal and dendritic filopodia induction.
Biological Process
Axon choice point recognition Source: GO_Central
Axon regeneration Source: GO_Central
Cell fate commitment Source: Ensembl
Glial cell differentiation Source: Ensembl
Protein kinase C-activating G protein-coupled receptor signaling pathway Source: ProtInc
Regulation of filopodium assembly Source: UniProtKB
Regulation of growth Source: UniProtKB-KW
Regulation of postsynaptic specialization assembly Source: Ensembl
Response to wounding Source: ProtInc
Tissue regeneration Source: GO_Central
Cellular Location
Cytoplasm; Cell membrane; Growth cone membrane; Filopodium membrane; Synapse; Perikaryon; Dendrite; Axon. Cytoplasmic surface of growth cone and synaptic plasma membranes.
PTM
Phosphorylated (By similarity). Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity (By similarity).
Palmitoylated by ZDHHC3 (By similarity). Palmitoylation is regulated by ARF6 and is essential for plasma membrane association and axonal and dendritic filopodia induction (PubMed:14978216). Deacylated by LYPLA2 (PubMed:21152083).

Anti-GAP43 antibodies

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Mouse Anti-GAP43 Recombinant Antibody (CBFYH-3423) (CBMAB-H3969-FY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBFYH-3423
Application*: IH, WB

Mouse Anti-GAP43 Recombinant Antibody (CBFYH-0237) (CBMAB-H0349-FY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBFYH-0237
Application*: WB, IF

Mouse Anti-GAP43 Recombinant Antibody (CBLNG-181) (CBMAB-1560-CN)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: CBLNG-181
Application*: WB, E, IH

Mouse Anti-GAP43 Recombinant Antibody (Mix) (CBMAB-1559-CN)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: Mix
Application*: P, WB

Mouse Anti-GAP43 Recombinant Antibody (6F2) (CBMAB-AP2454LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 6F2
Application*: IHC, WB

Mouse Anti-GAP43 Recombinant Antibody (CAP807) (CBMAB-AP2453LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CAP807
Application*: ELISA, IHC, WB

Mouse Anti-GAP43 Recombinant Antibody (CBWJN-0606) (CBMAB-N0819-WJ)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse, Rat
Clone: CBWJN-0606
Application*: P, IH-F, WB

Mouse Anti-GAP43 Recombinant Antibody (CBXF-1000) (CBMAB-F1461-CQ)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-1000
Application*: WB, IC, P, C, E

Mouse Anti-GAP43 Monoclonal Antibody (GAP-8A12) (CBMAB-1320-YC)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rat, Mouse, Chicken, Human, Snake
Clone: GAP-8A12
Application*: C, P, WB

Mouse Anti-GAP43 Recombinant Antibody (CB254A) (CBMAB-CA254LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CB254A
Application*: ELISA, WB, IHC

Mouse Anti-GAP43 Recombinant Antibody (GAP-8A12) (CBMAB-AO487LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Chicken, Human, Mouse, Rat
Clone: GAP-8A12
Application*: ELISA, WB, IHC

Mouse Anti-GAP43 Recombinant Antibody (CB223) (CBMAB-CS223LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CB223
Application*: WB, IHC

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-539) (CBMAB-G1927-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBLG1-539
Application*: WB

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-518) (CBMAB-G1906-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Mouse, Rat
Clone: CBLG1-518
Application*: WB

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-519) (CBMAB-G1907-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBLG1-519
Application*: IH, IP, WB

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-537) (CBMAB-G1925-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBLG1-537
Application*: IH, WB

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-536) (CBMAB-G1924-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Rat
Clone: CBLG1-536
Application*: E, C, P, WB

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-523) (CBMAB-G1911-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rat
Clone: CBLG1-523
Application*: C, P, WB

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-535) (CBMAB-G1923-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBLG1-535
Application*: WB

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-527) (CBMAB-G1915-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBLG1-527
Application*: WB

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-528) (CBMAB-G1916-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat
Clone: CBLG1-528
Application*: P, WB

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-534) (CBMAB-G1922-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBLG1-534
Application*: IC, IF, WB

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-532) (CBMAB-G1920-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Chicken, Human, Mouse, Rabbit, Rat, Snake
Clone: CBLG1-532
Application*: E, C, P, WB

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-2568) (CBMAB-G0166-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat, Mouse
Clone: CBLG1-2568
Application*: WB

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-034) (CBMAB-G0170-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Rat
Clone: CBLG1-034
Application*: E, IH, WB

Mouse Anti-GAP43 Recombinant Antibody (10K231) (CBMAB-G1888-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Rat, Chicken, Human, Mouse
Clone: 10K231
Application*: IH, WB

Mouse Anti-GAP43 Recombinant Antibody (13B824) (CBMAB-G1889-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Mouse, Rat
Clone: 13B824
Application*: IF, WB

Mouse Anti-GAP43 Recombinant Antibody (15H198) (CBMAB-G1890-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: 15H198
Application*: IC, IF, WB

Mouse Anti-GAP43 Recombinant Antibody (1G7) (CBMAB-G1891-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1G7
Application*: IH

Mouse Anti-GAP43 Recombinant Antibody (2Q55) (CBMAB-G1892-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Human
Clone: 2Q55
Application*: IH, IP, WB

Mouse Anti-GAP43 Recombinant Antibody (3C11) (CBMAB-G1893-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3C11
Application*: E, WB

Mouse Anti-GAP43 Recombinant Antibody (7B10) (CBMAB-G1895-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Chicken, Human, Mouse, Rabbit, Rat, Reptile
Clone: 7B10
Application*: E, IH, WB

Mouse Anti-GAP43 Recombinant Antibody (9G366) (CBMAB-G1896-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG
Specificity: Rat, Chicken, Human, Mouse
Clone: 9G366
Application*: IH, WB

Rabbit Anti-GAP43 Recombinant Antibody (D9C8) (CBMAB-G1897-LY)

Datasheet SDS
Target: GAP43
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: D9C8
Application*: WB

Mouse Anti-GAP43 Recombinant Antibody (GAP-7B10) (CBMAB-G1901-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Mouse, Rat, Chicken, Human, Cat, Snake
Clone: GAP-7B10
Application*: WB

Mouse Anti-GAP43 Recombinant Antibody (M333) (CBMAB-G1903-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Rat, Mouse
Clone: M333
Application*: WB

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-516) (CBMAB-G1904-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBLG1-516
Application*: IC, IF, WB

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-517) (CBMAB-G1905-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Rat
Clone: CBLG1-517
Application*: E, C, P, WB

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-520) (CBMAB-G1908-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-520
Application*: P, WB

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-521) (CBMAB-G1909-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgM
Specificity: Chicken
Clone: CBLG1-521
Application*: F

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-525) (CBMAB-G1913-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat
Clone: CBLG1-525
Application*: IH, IP, WB

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-529) (CBMAB-G1917-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Rat, Chicken, Human, Mouse, Rabbit, Snake
Clone: CBLG1-529
Application*: P/F, WB

Mouse Anti-GAP43 Recombinant Antibody (CBLG1-530) (CBMAB-G1918-LY)

Datasheet SDS
Target: GAP43
Host: Mouse
Antibody Isotype: IgG1
Specificity: Rat, Mouse
Clone: CBLG1-530
Application*: IF, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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