HLF

This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq]
Full Name
hepatic leukemia factor
Biological Process
Multicellular organism development Source: ProtInc
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of transcription by RNA polymerase II Source: GO_Central
Rhythmic process Source: UniProtKB-KW
Skeletal muscle cell differentiation Source: Ensembl
Cellular Location
Nucleus
Involvement in disease
A chromosomal aberration involving HLF is a cause of pre-B-cell acute lymphoblastic leukemia (B-ALL). Translocation t(17;19)(q22;p13.3) with TCF3.
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Anti-HLF antibodies

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Mouse Anti-HLF Antibody (1C5) (CBMAB-0474-YC)

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Target: HLF
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1C5
Application*: IP, WB, M
Datasheet SDS

Mouse Anti-HLF Recombinant Antibody (2C9) (CBMAB-A3948-LY)

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Target: HLF
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2C9
Application*: WB, E
Datasheet SDS

Mouse Anti-HLF Recombinant Antibody (1F12-1C4) (CBMAB-A3947-LY)

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Target: HLF
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1F12-1C4
Application*: WB, E
Datasheet SDS

Mouse Anti-HLF (AA 1-296) Recombinant Antibody (CBFYH-1482) (CBMAB-H2437-FY)

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Target: HLF
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-1482
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-HLF Recombinant Antibody (CBFYH-1480) (CBMAB-H2435-FY)

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Target: HLF
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-1480
Application*: WB, E, IF
Datasheet SDS

Mouse Anti-HLF Monoclonal Antibody (CBFYH-3154) (CBMAB-H2434-FY)

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Target: HLF
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBFYH-3154
Application*: IP, WB
Datasheet SDS

Mouse Anti-HLF (AA 1-296) Monoclonal Antibody (CBFYH-3153) (CBMAB-H2433-FY)

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Target: HLF
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYH-3153
Application*: WB
Datasheet SDS

Mouse Anti-HLF Recombinant Antibody (CBFYH-1479) (CBMAB-H0708-FY)

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Target: HLF
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-1479
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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