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MGLL

This gene encodes a monoglyceride lipase, which catalyzes the hydrolysis of monoglycerides into fatty acids and glycerol.

Full Name

Monoglyceride Lipase

Function

Converts monoacylglycerides to free fatty acids and glycerol (PubMed:19029917, PubMed:20079333, PubMed:21049984, PubMed:22969151, PubMed:24368842).

Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (PubMed:19029917, PubMed:20079333, PubMed:21049984, PubMed:22969151, PubMed:24368842).

Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth (PubMed:20079333).

Biological Process

Acylglycerol catabolic process Source: UniProtKB
Arachidonic acid metabolic process Source: UniProtKB
Fatty acid biosynthetic process Source: UniProtKB-KW
Inflammatory response Source: ProtInc
Lipid metabolic process Source: ProtInc
Monoacylglycerol catabolic process Source: UniProtKB
Regulation of endocannabinoid signaling pathway Source: UniProtKB
Regulation of inflammatory response Source: UniProtKB
Regulation of sensory perception of pain Source: UniProtKB
Regulation of signal transduction Source: UniProtKB
Triglyceride catabolic process Source: UniProtKB-UniPathway

Cellular Location

Cytosol
Other locations
Membrane

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Anti-MGLL antibodies

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Rat Anti-MGLL Recombinant Antibody (CBFYA-0041) (CBMAB-X0060-FY)

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Target: MGLL

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: CBFYA-0041

Application*: F, C, FN, P

Rat Anti-MGLL Recombinant Antibody (CBFYM-2180) (CBMAB-M2362-FY)

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Target: MGLL

Host: Rat

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: CBFYM-2180

Application*: F, FN, C

Mouse Anti-MGLL Recombinant Antibody (CBFYM-2179) (CBMAB-M2361-FY)

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Target: MGLL

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBFYM-2179

Application*: F, IF, IH, WB

Mouse Anti-MGLL Recombinant Antibody (CBFYM-2178) (CBMAB-M2360-FY)

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Target: MGLL

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYM-2178

Application*: F, IF, IH, WB

Mouse Anti-MGLL Recombinant Antibody (CBFYM-2177) (CBMAB-M2359-FY)

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Target: MGLL

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBFYM-2177

Application*: F, P, WB

More Infomation

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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