MIXL1

Homeodomain proteins, such as MIXL1, are transcription factors that regulate cell fate during development (Hart et al., 2005 [PubMed 15982639]).[supplied by OMIM
Full Name
Mix1 homeobox-like 1 (Xenopus laevis)
Function
Transcription factor that play a central role in proper axial mesendoderm morphogenesis and endoderm formation. Required for efficient differentiation of cells from the primitive streak stage to blood, by acting early in the recruitment and/or expansion of mesodermal progenitors to the hemangioblastic and hematopoietic lineages. Also involved in the morphogenesis of the heart and the gut during embryogenesis. Acts as a negative regulator of brachyury expression (By similarity).
Biological Process
Cell migration involved in gastrulation Source: Ensembl
Digestive tract development Source: BHF-UCL
Endodermal cell differentiation Source: BHF-UCL
Endoderm development Source: BHF-UCL
Endoderm formation Source: GO_Central
Gastrulation Source: BHF-UCL
Heart development Source: BHF-UCL
Hematopoietic progenitor cell differentiation Source: BHF-UCL
Negative regulation of hematopoietic progenitor cell differentiation Source: BHF-UCL
Positive regulation of mesoderm development Source: BHF-UCL
Positive regulation of transcription by RNA polymerase II Source: BHF-UCL
Regulation of transcription by RNA polymerase II Source: GO_Central
Cellular Location
Nucleus
PTM
Phosphorylated at multiple sites.
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Anti-MIXL1 antibodies

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Mouse Anti-MIXL1 Recombinant Antibody (4D11) (CBMAB-A5490-LY)

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Target: MIXL1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4D11
Application*: WB, E
Datasheet SDS

Rat Anti-MIXL1 (AA 147-231) Recombinant Antibody (CBFYM-2249) (CBMAB-M2433-FY)

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Target: MIXL1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYM-2249
Application*: IC
Datasheet SDS

Mouse Anti-MIXL1 (AA 86-185) Recombinant Antibody (CBFYM-2248) (CBMAB-M2432-FY)

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Target: MIXL1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYM-2248
Application*: E, WB
Datasheet SDS

Mouse Anti-MIXL1 Recombinant Antibody (CBFYM-0649) (CBMAB-M0785-FY)

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Target: MIXL1
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-0649
Application*: E, WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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