SHPRH

SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5 (Unk et al., 2006 [PubMed 17108083]).
Full Name
SNF2 Histone Linker PHD RING Helicase
Function
E3 ubiquitin-protein ligase involved in DNA repair. Upon genotoxic stress, accepts ubiquitin from the UBE2N-UBE2V2 E2 complex and transfers it to 'Lys-164' of PCNA which had been monoubiquitinated by UBE2A/B-RAD18, promoting the formation of non-canonical poly-ubiquitin chains linked through 'Lys-63'.
Biological Process
Biological Process cellular response to DNA damage stimulusManual Assertion Based On ExperimentIDA:MGI
Biological Process DNA repairIEA:UniProtKB-KW
Biological Process nucleosome assemblyIEA:InterPro
Biological Process protein polyubiquitinationManual Assertion Based On ExperimentIDA:FlyBase
Biological Process protein ubiquitinationTAS:Reactome
Cellular Location
nucleoplasm
nucleosome
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Anti-SHPRH antibodies

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Mouse Anti-SHPRH Recombinant Antibody (CBXS-3536) (CBMAB-S6265-CQ)

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Target: SHPRH
Host: Mouse
Specificity: Human
Clone: CBXS-3536
Application*: WB
Datasheet SDS

Mouse Anti-SHPRH Recombinant Antibody (CBXS-2160) (CBMAB-S4923-CQ)

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Target: SHPRH
Host: Mouse
Specificity: Human
Clone: CBXS-2160
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-SHPRH Recombinant Antibody (CBXS-5245) (CBMAB-S2460-CQ)

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Target: SHPRH
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5245
Application*: WB
Datasheet SDS

Mouse Anti-SHPRH Recombinant Antibody (CBXS-5217) (CBMAB-S2434-CQ)

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Target: SHPRH
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-5217
Application*: WB
Datasheet SDS

Mouse Anti-SHPRH Recombinant Antibody (CBXS-5160) (CBMAB-S2378-CQ)

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Target: SHPRH
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-5160
Application*: WB
Datasheet SDS

Mouse Anti-SHPRH Recombinant Antibody (CBXS-5063) (CBMAB-S2284-CQ)

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Target: SHPRH
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5063
Application*: WB
Datasheet SDS

Mouse Anti-SHPRH Recombinant Antibody (CBXS-4319) (CBMAB-S1564-CQ)

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Target: SHPRH
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-4319
Application*: DB, IC, WB
Datasheet SDS

Mouse Anti-SHPRH Recombinant Antibody (CBXS-4216) (CBMAB-S1468-CQ)

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Target: SHPRH
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBXS-4216
Application*: WB
Datasheet SDS

Mouse Anti-SHPRH Recombinant Antibody (CBXS-3967) (CBMAB-S1230-CQ)

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Target: SHPRH
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXS-3967
Application*: WB
Datasheet SDS

Mouse Anti-SHPRH Recombinant Antibody (CBXS-5727) (CBMAB-S0591-CQ)

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Target: SHPRH
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXS-5727
Application*: WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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