HKDC1

This gene encodes a member of the hexokinase protein family. The encoded protein is involved in glucose metabolism, and reduced expression may be associated with gestational diabetes mellitus. High expression of this gene may also be associated with poor prognosis in hepatocarcinoma.
Full Name
hexokinase domain containing 1
Function
Catalyzes the phosphorylation of hexose to hexose 6-phosphate, although at very low level compared to other hexokinases (PubMed:30517626).

Has low glucose phosphorylating activity compared to other hexokinases (PubMed:30517626).

Involved in glucose homeostasis and hepatic lipid accumulation. Required to maintain whole-body glucose homeostasis during pregnancy; however additional evidences are required to confirm this role (By similarity).
Biological Process
Cellular glucose homeostasis Source: UniProtKB
Glucose 6-phosphate metabolic process Source: UniProtKB
Glycolytic process Source: GO_Central
Hexose metabolic process Source: UniProtKB-UniPathway
Cellular Location
Mitochondrion membrane. The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrion.
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Anti-HKDC1 antibodies

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Mouse Anti-HKDC1 Recombinant Antibody (3A2) (CBMAB-A3930-LY)

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Target: HKDC1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3A2
Application*: WB, E
Datasheet SDS

Mouse Anti-HKDC1 Recombinant Antibody (4E8) (CBMAB-A3929-LY)

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Target: HKDC1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4E8
Application*: IP, E
Datasheet SDS

Mouse Anti-HKDC1 (AA 102-201) Recombinant Antibody (CBFYH-1243) (CBMAB-H2215-FY)

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Target: HKDC1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYH-1243
Application*: E, WB
Datasheet SDS

Mouse Anti-HKDC1 (AA 1-427) Recombinant Antibody (CBFYH-1242) (CBMAB-H2214-FY)

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Target: HKDC1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYH-1242
Application*: E, IP
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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