HKDC1

This gene encodes a member of the hexokinase protein family. The encoded protein is involved in glucose metabolism, and reduced expression may be associated with gestational diabetes mellitus. High expression of this gene may also be associated with poor prognosis in hepatocarcinoma.

hexokinase domain containing 1

Catalyzes the phosphorylation of hexose to hexose 6-phosphate, although at very low level compared to other hexokinases (PubMed:30517626).

Has low glucose phosphorylating activity compared to other hexokinases (PubMed:30517626).

Involved in glucose homeostasis and hepatic lipid accumulation. Required to maintain whole-body glucose homeostasis during pregnancy; however additional evidences are required to confirm this role (By similarity).

Cellular glucose homeostasis Source: UniProtKB
Glucose 6-phosphate metabolic process Source: UniProtKB
Glycolytic process Source: GO_Central
Hexose metabolic process Source: UniProtKB-UniPathway

Mitochondrion membrane. The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrion.