loading...

HPD

The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]

Full Name

4-hydroxyphenylpyruvate dioxygenase

Function

Key enzyme in the degradation of tyrosine.

Biological Process

L-phenylalanine catabolic process Source: UniProtKB-UniPathway
Tyrosine catabolic process Source: MGI

Cellular Location

Cytosol; Endoplasmic reticulum membrane; Extracellular exosome; Golgi membrane

Involvement in disease

Tyrosinemia 3 (TYRSN3):
An inborn error of metabolism characterized by elevations of tyrosine in the blood and urine, seizures and mild mental retardation.
Hawkinsinuria (HAWK):
An inborn error of tyrosine metabolism characterized by failure to thrive, persistent metabolic acidosis, fine and sparse hair, and excretion of the unusual cyclic amino acid metabolite, hawkinsin, in the urine.

View more

Anti-HPD antibodies

Products List

+ Filters

Loading...

Mouse Anti-HPD Recombinant Antibody (CBFYH-1882) (CBMAB-H2889-FY)

Compare

Target: HPD

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYH-1882

Application*: E, EC, WB

Mouse Anti-HPD Recombinant Antibody (CBFYH-1881) (CBMAB-H2888-FY)

Compare

Target: HPD

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBFYH-1881

Application*: WB, E

Mouse Anti-HPD (AA 160-270) Recombinant Antibody (CBFYH-1879) (CBMAB-H2886-FY)

Compare

Target: HPD

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYH-1879

Application*: WB

More Infomation

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

online inquiry

Online Inquiry