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Bone Marrow

Bone marrow is a kind of soft, spongy, gelatinous tissue filling in the cavities of bones. Bone marrow can be red or yellow, depending on whether it contains mainly hematopoietic tissue or fatty tissue. Bone marrow primarily filled with hematopoietic tissue undergoes hematopoiesis which keeps in red due to the presence of red blood cells, whereas bone marrow mainly containing fatty tissue does not undergo hematopoiesis keeps in yellow. Yellow bone marrow works primarily for the storage of fats however it could be converted into red marrow in certain conditions like fever or severe blood loss. Red bone marrow consists of a delicate, highly vascular fibrous tissue including hematopoietic stem cells from which the circulating blood cells are derived. It produces all of the blood cells in adults mainly including red blood cells, white blood cells, and platelets. Yellow bone marrow involves mesenchymal stem cells (also known as marrow stromal cells) which could develop into fat, bone as well as cartilage. There are many disease related to bone marrow such as leukemia, multiple myeloma, aplastic anemia. Because of the contribution to the blood circulatory system as well as immune system, the detection of the bone marrow plays an important role in diagnosing certain diseases, especially those related to blood and blood-forming organs.

For Research Use Only. Not For Clinical Use.