Midbody Ring

Fig.1 Midbody ring. (https://v18.proteinatlas.org/learn/dictionary/cell/cytokinetic+bridge+7) Fig.1 Midbody ring¹.

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At the end of cytokinesis, the dividing cells are connected by an intercellular bridge, containing the midbody along with a single, densely ubiquitylated, the circular structure called the midbody ring (MR). MRs are large (about 1.5 μm), ring-like macromolecular assemblies that contain several proteins, including centriolin2, MKLP1 (ref. 7), the deubiquitylation enzyme USP8 (also known as UBPY), and the multifunctional anti-apoptotic ubiquitin ligase BRUCE3,9, which has a relative molecular mass of 528,000 (Mr 528K).

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