|  

Nuclear Speckles

Creative Biolabs provides a range comprehensive of recombinant antibodies used in the research of nuclear speckles.

Speckles are subnuclear structures that are enriched in pre-messenger RNA splicing factors and are located in the interchromatin regions of the nucleoplasm of mammalian cells. Under the fluorescence-microscope level they are observed as irregular, punctate structures, which vary in size and shape, and when examined by electron microscopy they are seen as clusters of interchromatin granules. The components exchange constantly between speckles and other nuclear locations, including active transcription sites, since the components are dynamic.