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Renal Cell Cancer

Fig.1 Renal cell carcinoma

Renal cell carcinoma (RCC) is a kind of kidney cancer that starts from the lining of the proximal convoluted tubule, which is a kind of the very small tubes in the kidney and is responsible for transporting primary urine. RCC is the overwhelming type of kidney cancer in adults, accounting for approximately 90–95% of cases. The body is particularly good at hiding the symptoms and as a result people with RCC often have advanced disease by the time it is diagnosed. The initial symptoms of RCC often include: flank pain (40%), fever (20%), weight loss (33%), blood in the urine (occurring in about 40% of affected persons at the time they first seek medical assistance), a mass in the flank or abdomen (25%), high blood pressure (20%), night sweats and feeling unwell. Some potential prognostic markers, like Lactate dehydrogenase A in clear cell, have been studied recently.