Migrasomes

Fig.1 Migrasomes. (Yu & Li, 2022) Fig.1 Migrasomes¹.

Creative Biolabs provides a comprehensive range of recombinant antibodies used in the research of migrasomes.

Migrasomes are a kind of organelle produced by migrating cells. They are formed on long tethers called retraction fibers (RFs), which are trailed behind the migrating cells. Migrasomes can exert their biological functions through three different modes of action. First, the migrasomes act as packets of information that can be transmitted to a spatially defined location to send a signal to the surrounding cells. Secondly, the migrasomes act as a garbage disposal mechanism by which damaged organelles are expelled from the cells. Finally, the migrasomes play a role in mediating the lateral or horizontal transfer of RNAs and proteins. Migrasomes are not only involved in embryonic development but also play an important role in other biological processes involving migrating cells, including immune response, angiogenesis, tissue regeneration, and tumor metastasis.

Reference