A glioma is a kind of tumor that originates in the spine or brain. It is called a glioma because it arises from glial cells. Gliomas make up about 30% of all brain and central nervous system tumors and about 80% of all malignant brain tumors. Symptoms of gliomas depend on which site of the central nervous system is affected. A brain glioma can cause vomiting, headaches, seizures, and cranial nerve disorders because of enhanced intracranial pressure. A glioma of the optic nerve can damage the eyesight. Spinal cord gliomas may cause weakness, pain or numbness in the extremities. Gliomas do not metastasize by the bloodstream, however they can spread via the cerebrospinal fluid and cause "drop metastases" to the spinal cord. The exact causes of gliomas are remained to be discovered. Some glioma markers like Serum GFAP autoantibody, have been studied recently.
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